Topazolin, a natural product isolated and purified from the roots of Yellow Lupin with weak fungitoxic activity, displays significant activity against Salmonella typhimurium ATCC 13311 with MIC values ranging from 2 to 8 ug/mL, and also shows in vitro free radical scavenging activities with IC50 values in the range of 0.18-0.56 mg/mL.

Sophoraisoflavone A, a natural product isolated and purified from the root exudates of white lupin, is an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, strongly inhibiting germ tube growth at 1.25 ug/disc. Sophoraisoflavone A is also a potential MRP inhibitor showing inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro.

2'-hydroxygenistein, a natural product isolated and purified from the roots of Lupinus mutabilis with antifungal activity, exhibits greater antiproliferative effects in MCF-7 human breast cancer cells than does genistein, and shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils in response to formyl-Met-Leu-Phe/cytochalasin B.

6,8-Diprenylgenistein is a natural product isolated and purified from the roots of Lupinus mutabilis with antimicrobial activity against Gram-negative and Gram-positive bacteria.