Cucurbitacin E是一种JAK2 和 STAT3的抑制剂，可抑制细胞周期蛋白B1/CDC2复合物的活性。

Cucurbitacin IIb是一种从 Hemsleya amabilis Diels 根茎中提取和纯化的天然产物。

Cucurbitacin D是 Trichosanthes kirilowii 的活性成分，可干扰 Hsp90 与辅因子 Cdc37 和 p23 的相互作用。作为炎性体激活剂，Cucurbitacin D 可诱导细胞周期阻滞和细胞凋亡，展现出抗肿瘤和抗炎特性。

Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells[1].

Chikusetsusaponin IVa a major active ingredient of triterpenoid saponins isolated and purified from the herbs of Hemsleya amabilis Diels,, exerts antithrombotic effects, including minor hemorrhagic events.