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dFKBP-1 is a selective and potent PROTAC degrader targeting on FKBP12 with DC50 value of 10nM. It was generated by linking FKBP12-directed ligand SLF with phthalimide to a CRBN ligand.
PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an VHL binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1].
Tags: FKBP12/PROTAC | PROTAC功能分子 | PROTAC Molecule | FKBP12/PROTAC 相关产品
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