Eriodictyol-7-O-glucoside, a natural product isolated and purified from the herbs of Dracocephalum rupestre, can activate Nrf2/ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic, suggesting that targeting the Nrf2/ARE pathway may be a promising approach for therapeutic intervention in stroke.

Luteollin 5-glucoside is a natural product isolated and purified from the herb of Dracocephalum ruyschiana L. with antioxidant activity, which can inhibit lipid peroxidation, and has DPPH radical-scavenging activity.

Drahebenine is a natural product isolated and purified from the aerial parts of Dracocephalum heterophyllum.