SC-26196 is a selective Delta 6 desaturase inhibitor with IC50 = 0.2 μM. It had pharmacokinetic and pharmacodynamic profiles in mice and showed antiinflammatory properties. It resulted in 36-37% fewer tumors in Apc(Min/+) mice and 35% decrease in primary tumor size in nude mice bearing HT-29 human colon cancer cell xenografts.