NSC228155 can enhance the tyrosine phosphorylation of EGFR via binding to the dimerization domain II. It blocks KIX-KID interaction as well (IC50 = 0.36 μM).

666-15是一种高效且选择性的CREB抑制剂，IC50为81 nM，在乳腺癌异种移植模型中抑制肿瘤生长。

Ingliforib is a glycogen phosphorylase inhibitor, with IC50s of 52, 352 and 150 nM for liver, muscle and brain glycogen phosphorylase, and has cardioprotective activity.

RWJ-56110 is a selective protease-activated receptor-1 (PAR1) antagonist. It blocks thrombin-induced platelet aggregation and activation of MAPK in HUVECs.