Brevilin A, a natural product isolated and purified from the herbs of Centipeda minima, is a strong impetus for the development of selective JAK-STAT inhibitors and therapeutic drugs in order to improve survival of patients with hyperactivated JAKs and STATs, and has antigiardial activity (IC50 = 16.1 μM) and was similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM).

Arnicolide D是一种从石胡荽中提取的倍半萜内酯，能够调节细胞周期，激活 caspase 信号通路，并抑制 PI3K/AKT/mTOR 和 STAT3 信号通路，展示了对鼻咽癌细胞生长的抑制作用。