Apelin-13 TFA是 G 蛋白偶联受体angiotensin II protein J (APJ) 的内源性配体，激活G蛋白偶联受体的 EC50 值为 0.37 nM。Apelin-13 TFA 具有扩张血管和降压作用。Apelin-13 TFA 也可用于 2 型糖尿病及代谢综合征的研究。

ML221 is a potent apelin receptor (APJ) antagonist with IC50s of 0.70 μM and 1.75 μM in cAMP and β-arrestin assay respectively.

[Pyr1]-Apelin-13 is a potent peptide apelin agonist with EC50 of 0.37 nM.

CY3-SE is a reactive dye for the labeling of amino-groups in biomolecules.

NRX-103094, a molecular glue, is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103094 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM.

Apelin-13 is the endogenous ligand of the orphan G protein-coupled receptor APJ, activates APJ receptor with an EC50 value of 0.37 nM in CHO cells[1][2].

MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart. It stimulates endothelial NOS phosphorylation and expression, promotes proliferation, and attenuates apoptosis of human pulmonary arterial endothelial cells in vitro.