AKR1C3-IN-1是一种高效选择性的 AKR1C3 抑制剂，IC₅₀ 值为 13 nM，适用于前列腺癌、乳腺癌等多种与 AKR1C3 活性相关的肿瘤研究。

Obafistat是一种高效的醛酮还原酶 AKR1C3 抑制剂，对人 AKR1C3 的 IC₅₀ 为 1.2 nM。该化合物广泛用于激素相关癌症和炎症性疾病的研究，具有潜在的药物开发价值。

1-Indanone is an oxidation product of Indan, a component of fuels, solvents, and varnishes. It is part of the steroid hormone biosynthesis, and arachidonic acid metabolism pathways.

Fidarestat is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat has the potential to treat diabetic disease.