SKF-83566是一种有效、口服活性强且可穿越血脑屏障的多巴胺 D1/D5 受体拮抗剂，同时也是竞争性多巴胺转运蛋白 (DAT) 抑制剂，IC50 为 5.7 μM，可用于研究帕金森氏症和尼古丁渴望的缓解。

NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 is a potent activator of adenylyl cyclase and increases intracellular cAMP. NKH477 exerts an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts[1].