Buprofezin 是一种广谱杀虫剂和几丁质合成抑制剂,针对同翅目害虫的发育阶段。Buprofezin 通过抑制细胞色素 c 氧化酶,促进能量代谢从有氧 TCA 循环和氧化磷酸化转向无氧糖酵解,并增加活性氧(ROS)的产生。
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
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快速发货 顺丰冷链运输,1-2 天到达
品质保证
技术支持
免费溶解
描述 | Buprofezin is recognized as a broad-spectrum insecticide and a chitin synthesis inhibitor that specifically targets developmental stages of coleopteran pests. It impacts cellular metabolism by shifting energy production from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Moreover, buprofezin increases the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase activity[1].[2]. |
体内研究 | In vivo, when administered orally in single doses of 46.3, 139, and 417 mg/kg, buprofezin is found to accumulate significantly in the liver (35.84%), brain (23.58%), stomach (21.94%), and kidney (18.64%)[1]. Additionally, these doses lead to elevated levels of malondialdehyde (MDA), particularly in the liver and brain, indicating increased oxidative stress[1]. |
体外研究 | In studies with HepG2 cells, buprofezin at concentrations of 100, 300, and 1000 µM significantly decreases cell viability[1]. At lower concentrations (3, 10, 30 µM; 24 h), buprofezin shifts energy metabolism in HepG2 cells from aerobic to anaerobic processes and inhibits the activity of Complex IV[1]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.27mL 0.65mL 0.33mL |
16.37mL 3.27mL 1.64mL |
32.74mL 6.55mL 3.27mL |
CAS号 | 69327-76-0 |
分子式 | C16H23N3OS |
分子量 | 305.438 |
别名 | 噻嗪酮 ;NNI-750 |
运输 | 蓝冰 |
存储条件 |
粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
DMSO: 105 mg/mL(343.77 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |