产品说明书

Buprofezin

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Chemical Structure| 69327-76-0 同义名 : 噻嗪酮 ;NNI-750
CAS号 : 69327-76-0
货号 : A518628
分子式 : C16H23N3OS
纯度 : 99%+
分子量 : 305.438
MDL号 : MFCD01681899
存储条件:

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(343.77 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Buprofezin is recognized as a broad-spectrum insecticide and a chitin synthesis inhibitor that specifically targets developmental stages of coleopteran pests. It impacts cellular metabolism by shifting energy production from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Moreover, buprofezin increases the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase activity[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.27mL

0.65mL

0.33mL

16.37mL

3.27mL

1.64mL

32.74mL

6.55mL

3.27mL

参考文献

[1]Ji X, et al. Potential hepatic toxicity of buprofezin at sublethal concentrations: ROS-mediated conversion of energy metabolism. J Hazard Mater. 2016 Dec 15;320:176-186.

[2]YoshioIzawa, et al. Inhibition of chitin biosynthesis by buprofezin analogs in relation to their activity controlling Nilaparvata lugens Stål. Pestic Biochem Physiol, 1985, 24(3): 343-347.