产品说明书

Maytansinol

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Chemical Structure| 57103-68-1 同义名 : Ansamitocin P-0;Antibiotic C-15003P0;maytansine derivative;NSC 239386
CAS号 : 57103-68-1
货号 : A880207
分子式 : C28H37ClN2O8
纯度 : 99%+
分子量 : 565.05
MDL号 : MFCD28144515
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 35 mg/mL(61.94 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Derived from Maytansine, Maytansinol (Ansamitocin P-0) possesses the capability to block tubulin polymerization and trigger cell apoptosis, showcasing antitumor efficacy suitable for oncological drug studies[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.77mL

0.35mL

0.18mL

8.85mL

1.77mL

0.88mL

17.70mL

3.54mL

1.77mL

参考文献

[1]Zafar S, et al. New insights into the anticancer therapeutic potential of maytansine and its derivatives. Biomed Pharmacother. 2023 Sep;165:115039.

[2]Edwards A, et al. Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells. Dis Model Mech. 2011 Jul;4(4):496-503.