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Cefaclor monohydrate

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Chemical Structure| 70356-03-5 同义名 : 头孢克洛一水合物 ;Cefaclor;Cefachlor;Cefaclorum
CAS号 : 70356-03-5
货号 : A862563
分子式 : C15H16ClN3O5S
纯度 : 99%
分子量 : 385.823
MDL号 : MFCD00071999
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Cefaclor is an orally active cephalosporin antibiotic that is well absorbed. It specifically targets penicillin-binding protein 3 (PBP3) and is used for the treatment and research of various bacterial infections such as respiratory tract infections, bacterial bronchitis, pharyngitis, and skin infections. It also has potential implications for studying depression[1].[2].[3].[4].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.59mL

0.52mL

0.26mL

12.96mL

2.59mL

1.30mL

25.92mL

5.18mL

2.59mL
参考文献

[1]引用1 ：Joo MK, et al. Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice. Sci Rep. 2023 Sep 19;13(1):15529.

[2]Li M, et al. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metab Dispos. 2006 Apr;34(4):547-55.

[3]Yoo HS, et al. Immunologic evaluation of immediate hypersensitivity to cefaclor. Yonsei Med J. 2014 Nov;55(6):1473-83.

[4]Neu HC, et al. Cefaclor: in vitro spectrum of activity and beta-lactamase stability. Antimicrob Agents Chemother. 1978 Apr;13(4):584-8.