产品说明书
AH-7614
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同义名 : | NSC 31171;N-xanthen-9-yl-p-Toluenesulfonamide |
| CAS号 : | 6326-06-3 | |
| 货号 : | A834543 | |
| 分子式 : | C20H17NO3S | |
| 纯度 : | 98% | |
| 分子量 : | 351.419 | |
| MDL号 : | MFCD00379273 | |
| 存储条件： |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(298.79 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | AH-7614 demonstrates potent and selective antagonism against FFA4 (GPR120), with pIC50 values of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. It exhibits selectivity for FFA4 over FFA1 (pIC50<4.6). AH-7614 effectively inhibits the actions of both the polyunsaturated ω-6 fatty acid linoleic acid and the synthetic FFA4 agonist[1].[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.85mL 0.57mL 0.28mL |
14.23mL 2.85mL 1.42mL |
28.46mL 5.69mL 2.85mL |
| 参考文献 |
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