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Dihydroevocarpine

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Chemical Structure| 15266-35-0 同义名 : -
CAS号 : 15266-35-0
货号 : A791952
分子式 : C23H35NO
纯度 : 98+%
分子量 : 341.53
MDL号 : -
存储条件：

粉末

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 16 mg/mL(46.85 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Dihydroevocarpine, a natural product isolated and purified from the fruits of Evodia rutaecarpa, is a moderate modulator of p-glycoprotein (p-gp) activity. Dihydroevocarpine also shows more potent inhibitory effects against MAO-B compared to MAO-A and potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 mg/mL.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.93mL

0.59mL

0.29mL

14.64mL

2.93mL

1.46mL

29.28mL

5.86mL

2.93mL
参考文献

[1]Yin YY, Yan LH, et al. [Simultaneous determination of seven constituents in Euodiae Fructus and two related species by HPLC] . Zhongguo Zhong Yao Za Zhi. 2014 Jul;39(14):2693-8. Chinese.

[2]Tang X, Huang Z, et al. Simultaneous determination of six bioactive compounds in Evodiae Fructus by high-performance liquid chromatography with diode array detection. J Chromatogr Sci. 2014 Feb;52(2):149-56.