产品说明书
Chrysin
 |
同义名 : | 5,7-Dihydroxyflavone;5,7-DHF;Galangin flavanone.;NP005901;NSC 407436 |
| CAS号 : | 480-40-0 | |
| 货号 : | A771467 | |
| 分子式 : | C15H10O4 | |
| 纯度 : | 98% | |
| 分子量 : | 254.238 | |
| MDL号 : | MFCD00006834 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(413 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
IP 2% DMSO+2% Tween80+30% PEG300+water 2 mg/mL clear PO 0.5% CMC-Na 46 mg/mL suspension |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Chrysin, found in passion flowers, honey, and propolis, acts as a potential therapeutic and preventive agent against various human cancers, including ovarian cancer. It inhibits ovarian cancer cell proliferation and induces cell death by increasing ROS production, cytoplasmic Ca2+ levels, and inducing loss of mitochondrial membrane potential. Chrysin activates both MAPK and PI3K/AKT pathways, suppresses tumor growth by regulating Wnt and NF-κB signaling, and stimulates phosphorylation of AKT and P70S6K proteins[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.93mL 0.79mL 0.39mL |
19.67mL 3.93mL 1.97mL |
39.33mL 7.87mL 3.93mL |
| 参考文献 |
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