产品说明书
PD176252
 |
同义名 : | - |
| CAS号 : | 204067-01-6 | |
| 货号 : | A770674 | |
| 分子式 : | C32H36N6O5 | |
| 纯度 : | 98% | |
| 分子量 : | 584.665 | |
| MDL号 : | MFCD09971099 | |
| 存储条件： |
粉末 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 110 mg/mL(188.14 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.71mL 0.34mL 0.17mL |
8.55mL 1.71mL 0.86mL |
17.10mL 3.42mL 1.71mL |
