产品说明书
Poly(vinylpyrrolidone)–Iodine complex
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同义名 : | 聚乙烯吡咯烷酮碘;聚乙烯吡酮磺;聚乙烯吡咯烷酮碘络合物 ;Povidone iodine;iodopovidone;Polyvinylpyrrolidone-Iodine;NSC 26245;Isodine;PVP-I;PVP iodine;Betadine |
| CAS号 : | 25655-41-8 | |
| 货号 : | A766302 | |
| 分子式 : | (C6H9NO)x.xI2 | |
| 纯度 : | Available Iodine 9-12% | |
| 分子量 : | 0 | |
| MDL号 : | MFCD00084483 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,Room temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 14 mg/mL，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 2 mg/mL，配合低频超声助溶 |
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| 动物实验配方： |
| 生物活性 | |||
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| 描述 | Povidone Iodine (PVP-I) is an antiseptic used for skin disinfection before and after surgery. Povidone iodine displays excellent antibacterial activity which can against MRSA (meticillin-resistant) and MSSA (meticillin-susceptible) strains with MICs (minimum inhibitory concentration) of 31.25 mg/L and 7.82 mg/L, respectively. Treatment of the cells with Povidone iodine (PVP-I) at a dilution of 1:32 causes a sharp reduction in cell viability by 90-95% on all testing cell lines[3]. Povidone iodine has many characteristics that position it extraordinarily well for wound healing, including its broad antimicrobial spectrum, lack of resistance, efficacy against biofilms, good tolerability and its effect on excessive inflammation.[4]. SARS-CoV-2 virus was completely inactivated by PVP-I oral antiseptic rinse in vitro, at the lowest concentration of 0.5 % and at the lowest contact time of 15 seconds[5]. Nasal and oral PVP-I antiseptic solutions are effective at inactivating the SARS-CoV-2 at a variety of concentrations after 60-second exposure times[6]. | ||
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