产品说明书
Eltrombopag Olamine
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同义名 : | 艾曲泊帕乙醇胺盐 ;Eltrombopag diethanolamine salt;SB-497115GR;SB497115，SB-497115-GR |
| CAS号 : | 496775-62-3 | |
| 货号 : | A759657 | |
| 分子式 : | C29H36N6O6 | |
| 纯度 : | 98% | |
| 分子量 : | 564.633 | |
| MDL号 : | - | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(88.55 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia and the research of cardiovascular[1].[2].[3].[4].[5]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT01830660 | Healthy | Phase 1 | Completed | - | China, Sichuan ... 展开 >> West China Hospital, Sichuan University Chengdu, Sichuan, China 收起 << |
| NCT02158936 | Thrombocytopaenia | Phase 3 | Terminated | - | - |
| NCT01957176 | Thrombocytopaenia | Phase 4 | Active, not recruiting | January 1, 2024 | Argentina ... 展开 >> Novartis Investigative Site La Plata, Buenos Aires, Argentina, B1900AXI Belgium Novartis Investigative Site Leuven, Belgium, 3000 China Novartis Investigative Site Shanghai, China, 200025 France Novartis Investigative Site Paris Cedex 12, France, 75571 Greece Novartis Investigative Site Athens, Greece, 11527 Novartis Investigative Site Heraklion, Crete, Greece, 71201 Hong Kong Novartis Investigative Site Shatin, Hong Kong Hungary Novartis Investigative Site Debrecen, Hungary, 4012 Ireland Novartis Investigative Site Tullamore, Ireland Israel Novartis Investigative Site Tel Aviv, Israel, 64239 Korea, Republic of Novartis Investigative Site Seoul, Korea, Republic of, 136-705 Netherlands Novartis Investigative Site Amsterdam, Netherlands, 1081 HV Peru Novartis Investigative Site San Isidro, Lima, Peru, Lima 27 Poland Novartis Investigative Site Chorzow, Poland, 41-500 Romania Novartis Investigative Site Bucharest, Romania, 022328 Tunisia Novartis Investigative Site Montfleury, Tunisia, 1008 Novartis Investigative Site Sousse, Tunisia, 4000 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.77mL 0.35mL 0.18mL |
8.86mL 1.77mL 0.89mL |
17.71mL 3.54mL 1.77mL |
| 参考文献 |
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