产品说明书

Tiaprofenic Acid

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Chemical Structure| 33005-95-7 同义名 : RU 15060;Tiaprofensaeure;trade names Surgam, Surgamyl and Tiaprofen.;Tiaprofen;Acido tiaprofenico
CAS号 : 33005-95-7
货号 : A758829
分子式 : C14H12O3S
纯度 : 98%
分子量 : 260.308
MDL号 : MFCD00866089
存储条件:

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(403.37 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Tiaprofenic acid is an orally active non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties. Tiaprofenic acid inhibits prostaglandin synthesis by inhibiting COX. Tiaprofenic acid is used in the treatment of rheumatic diseases [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.84mL

0.77mL

0.38mL

19.21mL

3.84mL

1.92mL

38.42mL

7.68mL

3.84mL

参考文献

[1]G L Plosker, et al. Tiaprofenic Acid. A Reappraisal of Its Pharmacological Properties and Use in the Management of Rheumatic Diseases. Drugs. 1995 Dec;50(6):1050-75.

[2]L J Benincosa, et al. Tiaprofenic Acid Inhibits the Renal Reabsorption of Sulfate in Rats. Prostaglandins Leukot Essent Fatty Acids. 1993 Jul;49(1):503-8.