产品说明书

Oxytetracycline HCI

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Chemical Structure| 2058-46-0 同义名 : 盐酸土霉素 ;OTC;Oxycycin;Terramycin;Stevacin
CAS号 : 2058-46-0
货号 : A734976
分子式 : C22H25ClN2O9
纯度 : 98%
分子量 : 496.895
MDL号 : MFCD00135815
存储条件:

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 300 mg/mL(603.75 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Oxytetracycline hydrochloride, a member of the tetracycline class of antibiotics, effectively inhibits both Gram-negative and Gram-positive bacteria. It functions as a protein synthesis inhibitor by preventing the binding of aminoacyl-tRNA to the mRNA-ribosome complex and also exhibits anti-HSV-1 (Herpes Simplex Virus-1) activity[1].[2].[3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.01mL

0.40mL

0.20mL

10.06mL

2.01mL

1.01mL

20.12mL

4.02mL

2.01mL

参考文献

[1]Elia AC, et al. Transferability of oxytetracycline (OTC) from feed to carp muscle and evaluation of the antibiotic effects on antioxidant systems in liver and kidney. Fish Physiol Biochem. 2014 Aug;40(4):1055-68.

[2]Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285(36):27509-15.

[3]Oguz Guvenmez, et al. A New Treatment Method for Herpes Simplex Virus Type 1-related Skin Lesions. Scientific & Academic. 2019; 8(1): 6-8.