产品说明书
Patchouli alcohol
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同义名 : | 广藿香醇 ;Patchoulol;Patchouli camphor;(-)-Patchouli Alcohol |
| CAS号 : | 5986-55-0 | |
| 货号 : | A732149 | |
| 分子式 : | C15H26O | |
| 纯度 : | 98%+ | |
| 分子量 : | 222.366 | |
| MDL号 : | MFCD00209526 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(472.19 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO 无水乙醇: 20 mg/mL(89.94 mM)，配合低频超声助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇 |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Patchouli alcohol (PA) is a natural tricyclic sesquiterpene extracted from Pogostemon cablin (Blanco) Benth, and exhibits anti-Helicobacter pylori and anti-inflammatory properties. Treatment with PA for 2 weeks exhibited highly efficient protective effect against H. pylori-induced gastritis and related damages[3]. PA ameliorated DSS-induced (dextran sulfate sodium) mice acute colitis by suppressing inflammation, maintaining the integrity of intestinal epithelial barrier, inhibiting cell death signaling, and suppressing tryptophan catabolism[4]. Treatment of patchouli alcohol reduced lipid accumulation in 3T3-L1 adipocytes in a dose-dependent manner without toxicity. Oral gavage of patchouli alcohol led to a significant reduction of body weight and fat accumulation in the mice fed with HFD (high-fat diet)[5]. PA significantly inhibited different IAV (anti-influenza virus) strains multiplication in vitro, and may block IAV infection through inactivating virus particles directly and interfering with some early stages after virus adsorption[6]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
4.50mL 0.90mL 0.45mL |
22.49mL 4.50mL 2.25mL |
44.97mL 8.99mL 4.50mL |
| 参考文献 |
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