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Blarcamesine HCl

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Chemical Structure| 195615-84-0 同义名 : Anavex 2-73;Blarcamesine hydrochloride;AE-37 hydrochloride;AVex-73 hydrochloride;Anavex 2-73 HCl
CAS号 : 195615-84-0
货号 : A711600
分子式 : C19H24ClNO
纯度 : 98%
分子量 : 317.85
MDL号 : MFCD30146449
存储条件：

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 25 mg/mL(78.65 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(314.61 mM)，配合低频超声助溶
动物实验配方：
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.15mL

0.63mL

0.31mL

15.73mL

3.15mL

1.57mL

31.46mL

6.29mL

3.15mL
参考文献

[1]Villard V, et al. Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative. J Psychopharmacol. 2011 Aug;25(8):1101-17.

[2]Valentine Lahmy, et al. Blockade of Tau Hyperphosphorylation and Aβ1-42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic andσ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer's Disease. Neuropsychopharmacology. 2013 Aug; 38(9): 1706-1723.