产品说明书
Montelukast
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同义名 : | MK0476 free base;MK-476;MK0476 |
| CAS号 : | 158966-92-8 | |
| 货号 : | A707632 | |
| 分子式 : | C35H36ClNO3S | |
| 纯度 : | 99% | |
| 分子量 : | 586.183 | |
| MDL号 : | MFCD05662278 | |
| 存储条件： |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 250 mg/mL(426.49 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Montelukast (MK0476 free base) is a potent, selective, and orally active antagonist of the cysteinyl leukotriene receptor 1 (CysLT1). It finds utility in asthma and liver injury research. Moreover, Montelukast exhibits antioxidant properties in intestinal ischemia-reperfusion injury, potentially mitigating cardiac damage. Additionally, it reduces eosinophil infiltration in asthmatic airways and holds promise for COVID-19 research[1][2][3][4]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.71mL 0.34mL 0.17mL |
8.53mL 1.71mL 0.85mL |
17.06mL 3.41mL 1.71mL |
| 参考文献 |
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