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Hyperforin

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Chemical Structure| 11079-53-1 同义名 : -
CAS号 : 11079-53-1
货号 : A688823
分子式 : C35H52O4
纯度 : 99+%
分子量 : 536.785
MDL号 : MFCD01861497
存储条件:

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Hyperforin, a pharmacologically active component of the medicinal plant Hypericum perforatum (St. John's wort), has been shown to be neuroprotective against acute ischemic stroke.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02505191 Healthy Phase 1 Completed - Germany ... 展开 >> Nuvisan GmbH Neu-Ulm, Germany 收起 <<
NCT01726764 Type 2 Diabetes ... 展开 >> Depression 收起 << Phase 1 Completed - Denmark ... 展开 >> Department of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark Odense, Denmark, DK-5000 收起 <<
NCT01921881 Type 2 Diabetes Phase 1 Completed - Denmark ... 展开 >> Department of Clinical Pharmacology, Institute of Public Health, University of Southern Denmark Odense C, Denmark, DK-5000 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.86mL

0.37mL

0.19mL

9.31mL

1.86mL

0.93mL

18.63mL

3.73mL

1.86mL

参考文献

[1]Imreova P, Feruszova J, et al. Hyperforin Exhibits Antigenotoxic Activity on Human and Bacterial Cells. Molecules. 2017 Jan 21;22(1). pii: E167.

[2]Kwon J, Oh KS, et al. Estrogenic Activity of Hyperforin in MCF-7 Human Breast Cancer Cells Transfected with Estrogen Receptor. Planta Med. 2016 Nov;82(16):1425-1430.