生物活性 | |||
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描述 | UPGL00004 is a potent, variant glutaminase C (GAC) inhibitor (IC50 = 29 nM; Kd = 27 nM). UPGL00004 strongly inhibits the proliferation of highly aggressive triple-negative breast cancer cell lines [1].The IC50 values of the inhibitory effects of UPGL00004 on MDA-MB-231, HS578T and TSE cells were 70 nM, 129 nM and 262 nM, respectively[1] . |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.87mL 0.37mL 0.19mL |
9.35mL 1.87mL 0.94mL |
18.70mL 3.74mL 1.87mL |
参考文献 |
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