产品说明书
Ethynylestradiol
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同义名 : | 乙炔基雌二醇 ;17α-Ethynylestradiol;Ethinylestradiol;Progynon C;Brand of Ethinyl Estradiol;Organon;Microfollin Forte;Ginestrene;Ethinyloestradiol;Ethynyl E2;Ethynyl 17β-Oestradiol;Ethynyl 17β-Estradiol;Ethynyl β-Estradiol |
| CAS号 : | 57-63-6 | |
| 货号 : | A638512 | |
| 分子式 : | C20H24O2 | |
| 纯度 : | 98% | |
| 分子量 : | 296.403 | |
| MDL号 : | MFCD00003690 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(354.25 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Ethinyl estradiol, also called 17α-Ethynyl estradiol, is contained in many oral contraceptives. The estradiol and progestin included in oral contraceptives prevent pregnancy by inhibiting the release of luteinizing hormone and follicle stimulating hormone from the pituitary gland, which prevents ovulation, changes the lining of the uterus to inhibit implantation, and alters the cervical mucus to prevent sperm from entering[3]. Neonatal exposure to Ethinyl estradio (low: 20 and high: 2000 g/kg) induced an abnormal estrous cycle during postnatal day 171–190 in low-dose group and postnatal day 126–145 in high-dose group[4]. Ethinyl estradiol at the dose of 5.0 μg/rat induced a decline in immobility behavior (p < 0.001) and an increase in both swimming (p < 0.04) and climbing (p < 0.001) behaviors compared with the control group[5]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.37mL 0.67mL 0.34mL |
16.87mL 3.37mL 1.69mL |
33.74mL 6.75mL 3.37mL |
| 参考文献 |
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