生物活性 | |||
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描述 | ND-646 simultaneously inhibits ACC1 and ACC2, thus preventing ACC2 from compensating for the inhibition of ACC1. ND-646 inhibits the dimerization of the hACC2-BC domain under native conditions. In a cell-free system, ND-646 inhibits the enzymatic activity of hACC1 with an IC50 of 3.5 nM and hACC2 with an IC50 of 4.1 nM[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.76mL 0.35mL 0.18mL |
8.79mL 1.76mL 0.88mL |
17.59mL 3.52mL 1.76mL |
参考文献 |
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