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Octanoic acid

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Chemical Structure| 124-07-2 同义名 : 正辛酸 ;Caprylic acid;C8:0 Fatty acid;Octylic acid;Octoic acid;Octic acid;Caprylsaeure
CAS号 : 124-07-2
货号 : A627710
分子式 : C8H16O2
纯度 : 95%
分子量 : 144.211
MDL号 : MFCD00004429
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(728.1 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Octanoic acid, also known as Caprylic acid, is an oily substance characterized by a slightly unpleasant, rancid taste. It finds widespread commercial use in creating esters for perfumery and in dye manufacturing. Additionally, Octanoic acid serves as a tremor-suppressing agent[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.93mL

1.39mL

0.69mL

34.67mL

6.93mL

3.47mL

69.34mL

13.87mL

6.93mL

参考文献

[1]Nahab FB, et al. Octanoic acid suppresses harmaline-induced tremor in mouse model of essential tremor. Neurotherapeutics. 2012 Jul;9(3):635-8.

[2]Joniec-Maciejak I, et al. Octanoic acid prevents reduction of striatal dopamine in the MPTP mouse model of Parkinson's disease. Pharmacol Rep. 2018 Oct;70(5):988-992.

[3]Kadota Y, et al. Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. Metabolism. 2015 Sep;64(9):1157-64.

[4]Leem J, et al. Octanoic acid potentiates glucose-stimulated insulin secretion and expression of glucokinase through the olfactory receptor in pancreatic β-cells. Biochem Biophys Res Commun. 2018 Sep 3;503(1):278-284.

[5]Kamata Y, et al. Induction of neurite outgrowth in PC12 cells by the medium-chain fatty acid octanoic acid. Neuroscience. 2007 May 25;146(3):1073-81.