生物活性 | |||
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描述 | PF 750 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH), showing variable IC50 values ranging from 16.2 to 595 nM depending on different pre-incubation times. This variability highlights its covalent mechanism of action, specifically targeting and modifying the enzyme's active site serine nucleophile[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.89mL 0.58mL 0.29mL |
14.47mL 2.89mL 1.45mL |
28.95mL 5.79mL 2.89mL |
参考文献 |
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