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Agnuside

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Chemical Structure| 11027-63-7 同义名 : 牡荆油 ;Agnoside
CAS号 : 11027-63-7
货号 : A604827
分子式 : C22H26O11
纯度 : 99%
分子量 : 466.435
MDL号 : MFCD00210471
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(225.11 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Agnuside, a natural product isolated and purified from the herbs of Vitex negundo L., has anti-arthritic activity. Agnuside shows inhibition of vascular permeability and leukocyte migration in vivo.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.14mL

0.43mL

0.21mL

10.72mL

2.14mL

1.07mL

21.44mL

4.29mL

2.14mL
参考文献

[1]Ramakrishna R, Bhateria M, et al. Plasma pharmacokinetics, bioavailability and tissue distribution of agnuside following peroral and intravenous administration in mice using liquid chromatography tandem mass spectrometry. J Pharm Biomed Anal. 2016 Jun 5;125:154-64.

[2]Pandey A, Bani S, et al. Anti-arthritic activity of agnuside mediated through the down-regulation of inflammatory mediators and cytokines. Inflamm Res. 2012 Apr;61(4):293-304.