产品说明书
ALK inhibitor 2
 |
同义名 : | - |
| CAS号 : | 761438-38-4 | |
| 货号 : | A524942 | |
| 分子式 : | C23H28ClN7O3S | |
| 纯度 : | 99%+ | |
| 分子量 : | 518.032 | |
| MDL号 : | MFCD23380589 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(96.52 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Anaplastic lymphoma kinase (ALK) encodes a highly conserved receptor tyrosine kinase (RTK) within the insulin receptor superfamily, comprised of an extracellular domain, a single-pass transmembrane region, and an intracellular kinase domain[2]. ALK inhibitors are potential anti-cancer drugs that act on tumours with variations of ALK such as an EML4-ALK[3]. ALK inhibitor 2 is a chemical analogue of LDK378 that is a potent ALK inhibitor[4]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.93mL 0.39mL 0.19mL |
9.65mL 1.93mL 0.97mL |
19.30mL 3.86mL 1.93mL |
| 参考文献 |
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