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N-Acetyl-L-cysteine ethyl ester

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Chemical Structure| 59587-09-6 同义名 : N-Acetylcysteine ethyl ester;NACET;NAC ethyl ester
CAS号 : 59587-09-6
货号 : A467353
分子式 : C7H13NO3S
纯度 : 95%
分子量 : 191.248
MDL号 : MFCD09954466
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(261.44 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(522.88 mM)
动物实验配方：
生物活性
描述 N-Acetyl-L-cysteine ethyl ester is a derivative of N-acetyl-L-cysteine (NAC) characterized by enhanced cell permeability. It generates NAC and cysteine upon metabolism. Moreover, it elevates circulating hydrogen sulfide (H2S) levels, serving as an H2S producer. This compound holds promise as a substitute for NAC in mucolytic therapy and as a glutathione-related antioxidant [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.23mL

1.05mL

0.52mL

26.14mL

5.23mL

2.61mL

52.29mL

10.46mL

5.23mL
参考文献

[1]Daniela Giustarini, et al. N-Acetylcysteine ethyl ester (NACET): a novel lipophilic cell-permeable cysteine derivative with an unusual pharmacokinetic feature and remarkable antioxidant potential. Biochem Pharmacol. 2012 Dec 1;84(11):1522-33.