Minaprine dihydrochloride

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Chemical Structure| 25953-17-7 同义名 : -
CAS号 : 25953-17-7
货号 : A458274
分子式 : C17H24Cl2N4O
纯度 : 99%+
分子量 : 371.305
MDL号 : MFCD00083410
存储条件：

Pure form Inert atmosphere,Room Temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(282.79 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(269.32 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Minaprine dihydrochloride is a reversible inhibitor of MAO-A, also weakly inhibits acetylcholinesterase and is an antidepressant for treatment of depression.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00940823 - Completed - -
NCT03499964 Urethral Stricture Not Applicable Recruiting November 2024 United States, Arkansas ... 展开 >> Arkansas Urology Recruiting Little Rock, Arkansas, United States, 72211 Contact: Katie O'Brien          Principal Investigator: Richard D'Anna, MD          Sub-Investigator: Keith Mooney, MD          Sub-Investigator: Edwin Diaz, MD          Sub-Investigator: Jeffrey Marotte, MD          Sub-Investigator: Megan Thomas, APRN          United States, Colorado Urology Associates, P.C. Recruiting Englewood, Colorado, United States, 80113 Contact: Lenden Neeper          Contact: Michelle Lexin          Principal Investigator: Barrett Cowan, MD          United States, Florida Advanced Urology Institute Recruiting Daytona Beach, Florida, United States, 32114 Contact: Jonelle Horsley          Principal Investigator: Jeffrey Dann, MD          United States, Maryland Chesapeake Urology Recruiting Hanover, Maryland, United States, 21076 Contact: Wendy Paxton          Principal Investigator: Kaiser Robertson, MD          Sub-Investigator: Robert Goldfarb, MD          Chesapeake Urology Research Recruiting Towson, Maryland, United States, 21204 Contact: Jacqueline Burmer          Principal Investigator: Richard Levin, MD          Sub-Investigator: Ronald Tutrone, MD          United States, Minnesota University of Minnesota Department of Urology Not yet recruiting Minneapolis, Minnesota, United States, 55445 Contact: Bethany Marlette          Principal Investigator: Sean Elliott, MD          United States, New Jersey Delaware Valley Urology Recruiting Voorhees, New Jersey, United States, 08043 Contact: Brianna Florentine          Principal Investigator: David Sussman, DO          United States, New York Western New York Urology Associates Recruiting Cheektowaga, New York, United States, 14225 Contact: Margaret Scott          Contact: Thomasina Smith          Principal Investigator: Kent Chevli, MD          Sub-Investigator: Peter Walter, MD          Columbia University Medical Center/New York-Presbyterian Hospital Not yet recruiting New York, New York, United States, 10032 Contact: Debduth Pijush          Principal Investigator: Steven Brandes, MD          Iris Cantor Men's Health Center Recruiting New York, New York, United States, 10065 Contact: Dominique Thomas          Principal Investigator: Alexis Te, MD          United States, Oregon Oregon Urology Institute Recruiting Springfield, Oregon, United States, 97477 Contact: Danna Cardenas          Principal Investigator: David DiMarco, MD          Sub-Investigator: Brian Mehlaff, MD          United States, South Carolina Carolina Urology Partners Recruiting West Columbia, South Carolina, United States, 29169 Contact: Pam Tims          Contact: Kristin Kennedy          Principal Investigator: Brian Willard, MD          Sub-Investigator: David Lamb, MD          Sub-Investigator: Keith Brightbill, MD          Sub-Investigator: Griffin Morrisson, MD          United States, Texas Urology San Antonio Recruiting San Antonio, Texas, United States, 78229 Contact: Jeannette Cruz          Principal Investigator: Christopher Cantrill, MD          Sub-Investigator: Daniel Saltzstein, MD          Sub-Investigator: Clayton Hudnall, MD          Sub-Investigator: Davie Talley, MD          United States, Virginia Urology of Virginia Recruiting Virginia Beach, Virginia, United States, 23462 Contact: Daniel Bekong          Principal Investigator: Ramon Virasoro, MD          Sub-Investigator: Jessica DeLong, MD          Sub-Investigator: Jeremy Tonkin, MD          Sub-Investigator: Kurt McCammon, MD          United States, Washington University of Washington Harborview Medical Center Recruiting Seattle, Washington, United States, 98104 Contact: Michael Donahue          Principal Investigator: Judith Hagedorn, MD          Sub-Investigator: Neils Johnsen, MD 收起 <<
NCT00852852 Cancer Not Applicable Completed - United States, Massachusetts ... 展开 >> Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, Washington University of Washington Medical Center Seattle, Washington, United States, 98115 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.69mL

0.54mL

0.27mL

13.47mL

2.69mL

1.35mL

26.93mL

5.39mL

2.69mL
参考文献

[1]Contreras JM, Rival YM, et al. Aminopyridazines as acetylcholinesterase inhibitors. J Med Chem. 1999 Feb 25;42(4):730-41.