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NADH disodium salt

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Chemical Structure| 606-68-8 同义名 : 还原型辅酶I 二钠(β-NADH) ;Disodium NADH
CAS号 : 606-68-8
货号 : A454463
分子式 : C21H27N7Na2O14P2
纯度 : 98%
分子量 : 709.405
MDL号 : MFCD00036200
存储条件：

粉末 Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(148.01 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(140.96 mM)
动物实验配方：
生物活性
描述 NADH disodium salt (Disodium NADH) functions as an orally active reduced coenzyme, a donor of ADP-ribose in ADP-ribosylation reactions, and a precursor for cyclic ADP-ribose. It plays a critical role as a regenerating electron donor in cellular energy metabolism processes, including glycolysis, β-oxidation, and the tricarboxylic acid (TCA) cycle[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.41mL

0.28mL

0.14mL

7.05mL

1.41mL

0.70mL

14.10mL

2.82mL

1.41mL
参考文献

[1]Ying W. NAD+ and NADH in cellular functions and cell death. Front Biosci. 2006 Sep 1;11:3129-48.

[2]Kimura N, et al. Comparison of metabolic fates of nicotinamide, NAD+ and NADH administered orally and intraperitoneally; characterization of oral NADH. J Nutr Sci Vitaminol (Tokyo). 2006 Apr;52(2):142-8.

[3]Wu K, et al. NADH and NRH as potential dietary supplements or pharmacological agents for early liver injury caused by acute alcohol exposure. Journal of Functional Foods, 2021, 87: 104852.