产品说明书

PF-04885614

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Chemical Structure| 1480833-70-2 同义名 : -
CAS号 : 1480833-70-2
货号 : A440213
分子式 : C13H14F3N3O
纯度 : 99%+
分子量 : 285.265
MDL号 : MFCD26792589
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(876.38 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 PF-04885614 is a potent NaV1.8 inhibitor derived from patent US2018328915. PF-04885614 has potential for the treatment of neurological and neurodevelopmental diseases[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.51mL

0.70mL

0.35mL

17.53mL

3.51mL

1.75mL

35.06mL

7.01mL

3.51mL
参考文献

[1]Brady MAHER, et al. Treatment of Neurological and Neurodevelopmental Diseases and Disorders Associated with Aberrant Ion Channel Expression and Activity. US20180328915A1.