产品说明书
Procyanidin A2
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同义名 : | (+)-Epicatechin-(4β-8,2β-O-7)-epicatechin;Procyanidol A2;Procyanidin dimer A2;Proanthocyanidin A2 |
| CAS号 : | 41743-41-3 | |
| 货号 : | A370837 | |
| 分子式 : | C30H24O12 | |
| 纯度 : | 99%+ | |
| 分子量 : | 576.504 | |
| MDL号 : | MFCD10566019 | |
| 存储条件： |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(182.13 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Procyanidin A2, a natural product isolated and purified from the rhizomes of Belamcanda chinensis (L.) DC., blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression, and has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT03553225 | Healthy Men and Women | Not Applicable | Recruiting | December 30, 2018 | United Kingdom ... 展开 >> King's College London Recruiting London, United Kingdom, SE1 9NH Contact: Mariam Bapir, M.Sc. 02074844162 ext 4162 mariam.bapir@kcl.ac.uk 收起 << |
| NCT01687114 | Urinary Tract Infection | Not Applicable | Completed | - | United States, Massachusetts ... 展开 >> Jean Mayer USDA Human Nutrition Research Center on Aging Boston, Massachusetts, United States, 02111 收起 << |
| NCT01099150 | Cardiovascular Disease | Not Applicable | Completed | - | United Kingdom ... 展开 >> University of Aberdeen Rowett Institute of Nutrition and Health Aberdeen, Aberdeenshire, United Kingdom, AB21 9SB 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.73mL 0.35mL 0.17mL |
8.67mL 1.73mL 0.87mL |
17.35mL 3.47mL 1.73mL |
| 参考文献 |
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