产品说明书

Tribendimidine

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Chemical Structure| 115103-15-6 同义名 : -
CAS号 : 115103-15-6
货号 : A357500
分子式 : C28H32N6
纯度 : 98%
分子量 : 452.594
MDL号 : MFCD00872821
存储条件：

粉末 Keep in dark place,Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(110.47 mM)，配合低频超声，并调节pH至3，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Tribendimidine, an orally active, broad-spectrum anthelmintic agent, is particularly effective against A. lumbricoides and N. americanus. It also acts as an L-type nicotinic acetylcholine receptor (nAChR) agonist[1][2][3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.21mL

0.44mL

0.22mL

11.05mL

2.21mL

1.10mL

22.09mL

4.42mL

2.21mL
参考文献

[1]Xiao SH, et al. Tribendimidine: a promising, safe and broad-spectrum anthelmintic agent from China. Acta Trop. 2005 Apr;94(1):1-14.

[2]Keiser J, et al. Evaluation of the in vivo activity of tribendimidine against Schistosoma mansoni, Fasciola hepatica, Clonorchis sinensis, and Opisthorchis viverrini. Antimicrob Agents Chemother. 2007 Mar;51(3):1096-8.

[3]Hu Y, et al. The new anthelmintic tribendimidine is an L-type (levamisole and pyrantel) nicotinic acetylcholine receptor agonist. PLoS Negl Trop Dis. 2009 Aug 11;3(8):e499.