产品说明书
4-Hydroxybenzyl alcohol
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同义名 : | NSC 227926;P-Methylolphenol;p-Hydroxybenzyl Alcohol;4-Methylolphenol |
| CAS号 : | 623-05-2 | |
| 货号 : | A337115 | |
| 分子式 : | C7H8O2 | |
| 纯度 : | 98% | |
| 分子量 : | 124.14 | |
| MDL号 : | MFCD00004658 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(402.77 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | 4-Hydroxybenzyl Alcohol (4-HBA), a kind of phenolic compounds, has been found in many plants, like Gastrodia elata Blume. It has many biological activities, such as anti-angiogenic, anti-inflammatory and anti-nociceptive activity [1] . In vitro studies, it was found that 4-HBA could significantly increase the astrocytes' ability of anti-oxidation by activation of Nrf2 and induction of HO-1. For example, after 6 hrs treatment with 100 μM 4-HBA, the survival rate of C6 cells in hydrogen peroxide (100 μM, 1 hr) would be increased from 54.2±0.7% to 85.9±1.5% [2] . In vivo studies, 4-HBA could be used in some neurological disorders. When given 50 and 100 mg/kg, the rats with cerebral injury would have better performance in many neurological indicators, such as smaller cerebral infarct size, little degenerated neurons and so on [3] . | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
8.06mL 1.61mL 0.81mL |
40.28mL 8.06mL 4.03mL |
80.55mL 16.11mL 8.06mL |
| 参考文献 |
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