产品说明书
Lersivirine
 |
同义名 : | UK-453061;UK-453,061 |
| CAS号 : | 473921-12-9 | |
| 货号 : | A306689 | |
| 分子式 : | C17H18N4O2 | |
| 纯度 : | 99%+ | |
| 分子量 : | 310.35 | |
| MDL号 : | MFCD16619314 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 50 mg/mL(161.11 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Lersivirine (UK-453061) is a potent and selective non-nucleoside reverse transcription inhibitor (NNRTI) with an IC50 of 119 nM, showing high efficacy against NNRTI-resistant viruses. It demonstrates strong antiretroviral effects against both wild-type HIV and clinically relevant NNRTI-resistant strains[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.22mL 0.64mL 0.32mL |
16.11mL 3.22mL 1.61mL |
32.22mL 6.44mL 3.22mL |
| 参考文献 |
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