Chlorhexidine Digluconate
产品说明书
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同义名 : | Chlorhexidine (digluconate) |
| CAS号 : | 18472-51-0 | |
| 货号 : | A286403 | |
| 分子式 : | C34H54Cl2N10O14 | |
| 纯度 : | 20 wt. % in H2O | |
| 分子量 : | 897.757 | |
| MDL号 : | MFCD00083599 | |
| 存储条件： |
Pure form Keep in dark place,Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 40 mg/mL(44.56 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 100 mg/mL(111.39 mM)，配合低频超声助溶 |
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| 动物实验配方： |
| 生物活性 | |||
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| 描述 | Chlorhexidine digluconate, a chlorophenyl biguanide, exhibits broad antibacterial activity against both Gram-positive and Gram-negative bacteria as well as fungi. It serves as a broad-spectrum antiseptic and disinfectant, effectively preventing and controlling infectious diseases in the oral cavity by eliminating bacteria present in saliva and on the tongue. Additionally, chlorhexidine digluconate acts as a cytotoxic agent, inducing both cell necrosis and apoptosis[1].[2].[3]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT00471783 | Gingivitis | Phase 3 | Completed | - | Canada, British Columbia ... 展开 >> Dr. Ian Low 2031 West 41st Avenue, Vancouver, British Columbia, Canada 收起 << |
| NCT01373632 | Coronary Artery Disease | Phase 4 | Unknown | September 2013 | China, Shanghai ... 展开 >> Ruijin Hospital, Shanghai Jiaotong University School of Medicine Recruiting Shanghai, Shanghai, China, 200025 Contact: WeiFeng Shen, MD, PhD 86-21-64370045 ext 665215 rjshenweifeng@yahoo.com.cn Contact: Xian Zhang, MD 86-21-64370045 ext 665215 Principal Investigator: WeiFeng Shen, MD, PhD Sub-Investigator: Qi Zhang, MD, PhD 收起 << |
| NCT01762904 | - | Completed | - | - | |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.11mL 0.22mL 0.11mL |
5.57mL 1.11mL 0.56mL |
11.14mL 2.23mL 1.11mL |
| 参考文献 |
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