产品说明书
Terazosin hydrochloride dihydrate
 |
同义名 : | 盐酸特拉唑嗪 二水合物 ;Terazosin HCl Dihydrate |
| CAS号 : | 70024-40-7 | |
| 货号 : | A281463 | |
| 分子式 : | C19H30ClN5O6 | |
| 纯度 : | 98% | |
| 分子量 : | 459.924 | |
| MDL号 : | MFCD00941408 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 30 mg/mL(65.23 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 12 mg/mL(26.09 mM)，配合低频超声助溶 |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Terazosin Hydrochloride Dihydrate is a α1-adrenoceptor blocker with a long lasting actionused for the improvement of urinary obstruction due to benign prostatic hyperplasia (BPH)[3].Terazosin therapy results in a significant reduction in blood pressure in patients with mild to moderate essential hypertension, with little influence on heart rate[4]. Terazosin alleviated organ damage and improved survival in rodent models of stroke and sepsis[5]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT00000620 | Atherosclerosis ... 展开 >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease 收起 << | Phase 3 | Completed | - | United States, Minnesota ... 展开 >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada 收起 << |
| NCT01323998 | - | Completed | - | - | |
| NCT03339258 | Stress Disorders, Post-Traumat... 展开 >>ic 收起 << | Phase 2 | Recruiting | June 2021 | United States, California ... 展开 >> San Francisco VA Medical Center Recruiting San Francisco, California, United States, 94121 Contact: Andrew Levihn-Coon, B.A. 415-221-4810 ext 23809 andrew.levihn-coon@va.gov 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.17mL 0.43mL 0.22mL |
10.87mL 2.17mL 1.09mL |
21.74mL 4.35mL 2.17mL |
| 参考文献 |
|---|