产品说明书
Pyridostatin
 |
同义名 : | RR82 |
| CAS号 : | 1085412-37-8 | |
| 货号 : | A280356 | |
| 分子式 : | C31H32N8O5 | |
| 纯度 : | 99%+ | |
| 分子量 : | 596.636 | |
| MDL号 : | MFCD25976689 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Pyridostatin stabilizes G-quadruplex DNA structures with a dissociation constant (Kd) of 490 nM, leading to growth arrest in human cancer cells by causing DNA damage dependent on both replication and transcription. It specifically targets the Src proto-oncogene, leading to reduced SRC protein levels and decreased SRC-dependent cell movement in human breast cancer cells[1][2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.68mL 0.34mL 0.17mL |
8.38mL 1.68mL 0.84mL |
16.76mL 3.35mL 1.68mL |
| 参考文献 |
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