产品说明书
Methylprednisolone succinate sodium
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同义名 : | 甲强龙琥珀酸钠 ;Methylprednisolone hydrogen succinate sodium;U-9088;6α-Methylprednisolone 21-hemisuccinate Sodium;Methylprednisolone sodium succinate |
| CAS号 : | 2375-03-3 | |
| 货号 : | A276578 | |
| 分子式 : | C26H33NaO8 | |
| 纯度 : | 98% | |
| 分子量 : | 496.525 | |
| MDL号 : | MFCD00152612 | |
| 存储条件： |
粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 25 mg/mL(50.35 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 50 mg/mL(100.7 mM)，配合低频超声助溶 |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | 6α-Methylprednisolone 21-hemisuccinate sodium salt is a glucocorticoid of slightly longer half-life than that of Prednisolone. It has potential uses in anti-inflammatory agents. Methylprednisolone aceponate (MPA) is a non-halogenated corticosteroid with a methyl group at C6, which confers higher intrinsic activity[3]. Methylprednisolone is a synthetic glucocorticoid with a potent and long-acting anti-inflammatory, anti-allergic and immunosuppressant. Methylprednisolone is used in many diseases, such as rheumatic diseases, autoimmune diseases, allergic, anaphylactic shock, asthma. Methylprednisolone was also used in patients with spinal cord injury, in order to minimize neurological damage[4]. There is no difference in efficacy and safety between oral methylprednisolone (oMP) and intravenous methylprednisolone (ivMP). In addition, both routes of administration are equally well tolerated and safe[5]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.01mL 0.40mL 0.20mL |
10.07mL 2.01mL 1.01mL |
20.14mL 4.03mL 2.01mL |
| 参考文献 |
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