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Amiodarone

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Chemical Structure| 1951-25-3 同义名 : -
CAS号 : 1951-25-3
货号 : A262295
分子式 : C25H29I2NO3
纯度 : 99%+
分子量 : 645.312
MDL号 : MFCD00242801
存储条件:

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01082055 - Completed - United Kingdom ... 展开 >> Univeristy of Dundee Dundee, United Kingdom, DD1 9SY 收起 <<
NCT03269383 Atrial Fibrillation Phase 4 Not yet recruiting December 2018 United States, Maine ... 展开 >> Maine Medical Center Not yet recruiting Portland, Maine, United States, 04102 Contact: Janelle Richard, BA, CCRP    207-662-2862    richaj3@mmc.org    Principal Investigator: Chris Connors, MD 收起 <<
NCT02248753 Atrial Fibrillation Not Applicable Active, not recruiting October 2019 Netherlands ... 展开 >> VU University Medical Center Amsterdam, Netherlands Amphia Hospital Breda, Netherlands Catharina Ziekenhuis Eindhoven, Netherlands Medisch Spectrum Twente Enschede, Netherlands University Medical Center Groningen Groningen, Netherlands Zuyderland Medical Center Heerlen, Netherlands Alrijne Hospital Leiderdorp, Netherlands Maastricht University Medical Center Maastricht, Netherlands St. Antonius Hospital Nieuwegein, Netherlands Franciscus Gasthuis Rotterdam, Netherlands Antonius Ziekenhuis Sneek, Netherlands HagaZiekenhuis The Hague, Netherlands St. Elisabeth - TweeSteden Hospital Tilburg, Netherlands Diakonessenhuis Utrecht, Netherlands VieCuri Medical Center Venlo, Netherlands 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.55mL

0.31mL

0.15mL

7.75mL

1.55mL

0.77mL

15.50mL

3.10mL

1.55mL

参考文献

[1]Simonen P, Lehtonen J,. Desmosterol accumulation in users of amiodarone. J Intern Med. 2017 Sep 1.

[2]Wang AG, Cheng HC. Amiodarone-Associated Optic Neuropathy: Clinical Review. Neuroophthalmology. 2016 Nov 18;41(2):55-58.