产品说明书

Aspartame

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Chemical Structure| 22839-47-0 同义名 : SC-18862;L-Aspartyl-L-Phenylalanine methyl ester;Aspartam.;Asp-phe-ome;Asp-Phe methyl ester;Nutrasweet
CAS号 : 22839-47-0
货号 : A247979
分子式 : C14H18N2O5
纯度 : 98%
分子量 : 294.303
MDL号 : MFCD00002724
存储条件:

粉末 Keep in dark place,Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 25 mg/mL(84.95 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 5 mg/mL(16.99 mM),配合低频超声助溶

动物实验配方:
生物活性
描述 Aspartame (SC-18862), a synthetic dipeptide methyl ester, is used as a non-nutritive synthetic sweetener[1].[2].
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02616484 Pyruvate Dehydrogenase Complex... 展开 >> Deficiency 收起 << Phase 3 Recruiting June 30, 2020 United States, California ... 展开 >> Children's Hospital of Orange County Not yet recruiting Orange, California, United States, 92868 Contact: Jose E Abdenur, MD    888-770-2462    jabdenur@choc.org    Stanford University Recruiting Stanford, California, United States, 94305 Contact: Gregory M Enns, M.B., Ch.B.    650-498-5798    greg.enns@stanford.edu    Contact: Thu Quan, MBA/HCM CCRC    650-736-8166    tquan@stanford.edu    United States, District of Columbia Children's National Medical Center Recruiting Washington, District of Columbia, United States, 20010 Contact: Andrea L Gropman, MD    202-476-6230    agropman@cnmc.org    United States, Florida University of Florida Recruiting Gainesville, Florida, United States, 32611 Contact: Richard Neiberger, MD    352-273-9014    neibere@peds.ufl.edu    Contact: Tracie Kurtz, RN    352-273-9014    tlkurtz@ufl.edu    United States, Ohio University Hospitals Cleveland Medical Center Recruiting Cleveland, Ohio, United States, 44106 Contact: Jirair Bedoayn, MD    215-844-3936    Jirair.Bedoyan@UHhospitals.org    Contact: Audrey Lynn, PhD    216-844-7124    audrey.lynn@uhhospitals.org    United States, Pennsylvania Children's Hospital of Philadelphia Recruiting Philadelphia, Pennsylvania, United States, 15224 Contact: Marni J Falk, MD    215-590-4564    falkm@email.chop.edu    Contact: Laura Dennis    267-426-0229    DENNISL@email.chop.edu    Children's Hospital of Pittsburgh Recruiting Pittsburgh, Pennsylvania, United States, 15224 Contact: Gerard Vockley, MD    412-692-5070    gerard.vockley@chp.edu    Contact: Jennifer Baker    412-692-6378    jennifer.baker@chp.edu    United States, Utah University of Utah Recruiting Salt Lake City, Utah, United States, 84113 Contact: Nicola Longo, MD, PhD    801-585-2457    NICOLA.LONGO@HSC.UTAH.EDU    Contact: Margaret Kuenzi, BS CCRC    801-585-9183    Margaret.Kuenzi@hsc.utah.edu    United States, Washington Seattle Children's Hospital Not yet recruiting Seattle, Washington, United States, 98105 Contact: Russell P Saneto, DO, PhD    206-987-2078    russ.saneto@seattlechildrens.org 收起 <<
NCT03708939 Glucose Intolerance ... 展开 >> Glucose, Low Blood Glucose, High Blood 收起 << Not Applicable Enrolling by invitation January 1, 2021 Israel ... 展开 >> Weizmann Institute of Science Reẖovot, Israel 收起 <<
NCT00654108 Escherichia Coli Infections Phase 1 Completed - United States, Ohio ... 展开 >> Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229-3039 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.40mL

0.68mL

0.34mL

16.99mL

3.40mL

1.70mL

33.98mL

6.80mL

3.40mL

参考文献

[1]Magnuson, B.A., et al., Aspartame: a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies. Crit Rev Toxicol, 2007. 37(8): p. 629-727.

[2]Humphries, P., E. Pretorius, and H. Naude, Direct and indirect cellular effects of aspartame on the brain. Eur J Clin Nutr, 2008. 62(4): p. 451-62.