产品说明书
Folinic acid
 |
同义名 : | 叶酸 ;leucovorin |
| CAS号 : | 58-05-9 | |
| 货号 : | A246299 | |
| 分子式 : | C20H23N7O7 | |
| 纯度 : | 99%+ | |
| 分子量 : | 473.439 | |
| MDL号 : | MFCD00867488 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 250 mg/mL(528.05 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Folinic acid (Leucovorin), a derivative of folic acid, serves as a rescue agent when administered alongside Methotrexate (MTX) to mitigate the toxicity induced by MTX treatment[1]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT01555190 | Polycystic Ovary Syndrome ... 展开 >> Hirsutism Menstrual Irregularity 收起 << | Not Applicable | Unknown | - | Italy ... 展开 >> Catholic University of Sacred Heart Recruiting Rome, Italy, 00168 Contact: Maurizio Guido, Medical Doctor 00390630156013 maurizioguido@libero.it Principal Investigator: Maurizio Guido, doctor 收起 << |
| NCT00633529 | Non-Small Cell Lung Cancer | Phase 1 | Completed | - | United States, Florida ... 展开 >> Cancer Centers of Florida Ocoee, Florida, United States, 34761 United States, Indiana Central Indiana Cancer Centers Indianapolis, Indiana, United States, 46219 United States, New York New York Oncology Hematology P.C. Albany, New York, United States, 12206 United States, Texas Mary Crowley Medical Research Center Dallas, Texas, United States, 75246 Cancer Therapy and Research Center San Antonio, Texas, United States, 78229 Tyler Cancer Center Tyler, Texas, United States, 75702 United States, Virginia Virginia Oncology Associates Norfolk, Virginia, United States, 23502 United States, Washington Northwest Cancer Specialists Vancouver, Washington, United States, 98684 Yakima Valley Memorial Hospital/North Shore Cancer Lodge Yakima, Washington, United States, 98902 收起 << |
| NCT00975364 | - | Completed | - | United Kingdom ... 展开 >> Institute of Food Research Norwich, Norfolk, United Kingdom, NR4 6JF 收起 << | |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.11mL 0.42mL 0.21mL |
10.56mL 2.11mL 1.06mL |
21.12mL 4.22mL 2.11mL |
| 参考文献 |
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