产品说明书
Eniluracil
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同义名 : | - |
| CAS号 : | 59989-18-3 | |
| 货号 : | A208918 | |
| 分子式 : | C6H4N2O2 | |
| 纯度 : | 98% | |
| 分子量 : | 136.108 | |
| MDL号 : | MFCD00871973 | |
| 存储条件： |
粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 16 mg/mL(117.55 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Eniluracil, also known as 5-Ethynyluracil, is an orally active dihydropyrimidine dehydrogenase (DPD) inhibitor. Eniluracil irreversibly inhibits DPD, increases the oral bioavailability of 5-fluorouracil to 100% and promotes the homogeneous absorption and toxicity of 5-fluorouracil. Eniluracil can be used in combination with fluoropyrimidines (e.g., 5-fluorouracil) in combination for cancer research[1][2].Eniluracil contains an alkyne group that can undergo copper-catalysed azide-alkyne cycloaddition (CuAAc) with molecules containing an azide moiety, and can therefore be used as a click chemistry reagent. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
7.35mL 1.47mL 0.73mL |
36.74mL 7.35mL 3.67mL |
73.47mL 14.69mL 7.35mL |
| 参考文献 |
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