Formononetin
产品说明书
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同义名 : | Biochanin B;Flavosil;Formononetol Formononetin;NSC 93360;Formononetol |
| CAS号 : | 485-72-3 | |
| 货号 : | A204811 | |
| 分子式 : | C16H12O4 | |
| 纯度 : | 98+% | |
| 分子量 : | 268.264 | |
| MDL号 : | MFCD00016948 | |
| 存储条件： |
Pure form Keep in dark place,Sealed in dry,Room Temperature In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 35 mg/mL(130.47 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Formononetin is the main compound of red clover plants, which belongs to herbal isoflavone. in vivo, formononetin could reduce the nephrotoxicity by decreasing the accumulation of cisplatin in renal tubular cells. After formononetin treatment (15, 50, 75 mg/kg), the levels of BUN(blood urea nitrogen) and creatinine were decreased in a dose-dependent manner. The mRNA level of Kim-1 in the kidneys was significantly elevated at 48 h[3]. Moreover, formononetin inhibits neuroinflammation by targeting NF-κB signalling pathway in BV2 microglia[4]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02174666 | Osteopenia Os... 展开 >>teoporosis 收起 << | Not Applicable | Unknown | September 2016 | Denmark ... 展开 >> Aarhus University Hospital Aarhus, Central Jutland Region, Denmark, 8000 收起 << |
| NCT01497977 | Low Serum Lipid Levels | Phase 4 | Completed | - | Serbia ... 展开 >> Ultramedica Clinic, American Medical Academy Belgrade, Serbia, 11000 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.73mL 0.75mL 0.37mL |
18.64mL 3.73mL 1.86mL |
37.28mL 7.46mL 3.73mL |
| 参考文献 |
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